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Complement C3 is a blood test that measures the activity of C3, a key protein in the complement system. The complement system consists of a group of proteins that circulate in the bloodstream and work alongside your immune system to fight infections and manage inflammation. By evaluating the level of C3 in your blood, this test can provide valuable information about your immune function and help identify inflammatory or autoimmune conditions. The test is typically performed as a single measurement of C3 levels.