This biopsy is typically performed on women who exhibit elevated levels of male hormones (androgens). It is also used to evaluate cases where a woman has a low sex drive or when a boy enters puberty prematurely. The procedure aids in the diagnosis of Congenital Adrenal Hyperplasia (CAH), a condition affecting the adrenal glands. Additionally, it is valuable for diagnosing Premature Adrenarche, a condition where puberty-like changes occur earlier than normal.