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The PSA Total (Prostate-Specific Antigen) test is a valuable tool for the early detection of prostate cancer, especially when used alongside a Digital Rectal Examination (DRE). It is particularly recommended for men over 50 years of age and those with two or more first-degree relatives affected by prostate cancer. The test is also essential for monitoring and managing prostate cancer in patients, helping to detect metastatic or persistent disease after treatment, whether through surgery or medication.

Increased PSA levels can indicate several prostate-related conditions, including:

• Prostate cancer: Elevated PSA levels are commonly associated with prostate cancer, though not exclusively.
• Benign Prostatic Hyperplasia (BPH): A non-cancerous enlargement of the prostate.
• Prostatitis: Inflammation of the prostate, often caused by infection.
• Genitourinary infections: Infections in the urinary tract or reproductive organs may also raise PSA levels.

Regular PSA testing, combined with clinical evaluation, helps in the early detection, follow-up, and management of prostate conditions, particularly cancer.