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The Serum-Ascites Albumin Gradient (SAAG) is a valuable tool in clinical practice, particularly in diagnosing the underlying cause of ascites. By measuring the difference between the albumin concentration in serum and ascitic fluid, the SAAG can help differentiate between ascites caused by portal hypertension and other etiologies, such as malignancy or infection. Compared to the older method of classifying ascitic fluid as a transudate or exudate, the SAAG has been shown to be a more reliable and accurate discriminator. This improved diagnostic ability helps guide appropriate treatment decisions, making the SAAG an essential metric in the evaluation of ascites.