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The Hepatitis B Core Antigen-Total Antibodies (Anti-HBc-Total) test measures the presence of antibodies against the core antigen of the Hepatitis B virus (HBV). The core antigen is a protein found inside the virus, and antibodies against it are produced by the immune system when the body is exposed to the virus.
Identify past or current infection: This test helps determine if a person has ever been infected with the Hepatitis B virus. The presence of Anti-HBc-Total suggests that a person has been exposed to HBV, either in the past or currently.
Assess immune status: A positive result can indicate either acute, chronic, or resolved infection depending on other factors (like the presence of HBsAg, the Hepatitis B surface antigen).
Diagnose chronic infection or exposure: The test is useful in diagnosing chronic Hepatitis B or distinguishing between those who are infected and those who have been vaccinated (as the vaccinated person would not have Anti-HBc antibodies, only the Anti-HBs surface antibodies).
This test is often part of a broader panel of Hepatitis B tests, which can include Hepatitis B Surface Antigen (HBsAg), Hepatitis B Surface Antibody (Anti-HBs), and Hepatitis B Viral Load (HBV DNA) for more comprehensive diagnosis and understanding of the infection stage.
Test Type: Blood
Reporting: Next Day
Free Home/Office Sample Collection
Fasting: Fasting is not mandatory
Best & Honest Price
One Prick Sample Collection Policy
Yes. Book home collection when ordering online or call our team. Trained phlebotomists visit your address at the scheduled slot.
Most routine tests are reported within 24–48 hours after sample validation. Specialized tests may take longer — see your booking confirmation.
CoreLab follows NABL-aligned quality-assured pathology processes with structured SOPs, trained collectors, and MD pathologist oversight.
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