Dihydrotestosterone (DHT) plays a crucial role in the development of male sex characteristics, particularly during fetal development, as it helps form the external genitalia. In adults, DHT is essential for maintaining male traits such as facial hair, a deep voice, and muscle growth.
In women, DHT is involved in the onset of puberty, contributing to the growth of body and pubic hair.
In males, around 70% of DHT is produced through the conversion of testosterone by the enzyme 5α-reductase in tissues like the prostate, testes, hair follicles, and adrenal glands. In females, most DHT is derived from androstenedione, a precursor hormone.
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