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When evaluating patients with signs and symptoms of autoimmune tissue disease and a positive test for antinuclear antibodies (A), it is important to consider specific autoantibodies, such as those against SS-A (Ro) and SS-B (La), which are commonly associated with various autoimmune conditions.
SS-A (Ro): This antigen, also known as Ro, is primarily linked to Sjogren's syndrome, where antibodies against SS-A are found in 40-95% of cases. They are also present in Systemic Lupus Erythematosus (SLE) (20-60%), primary biliary cirrhosis (about 20%), and occasionally in chronic active hepatitis.
SS-B (La): This antigen, also known as La, is similarly associated with Sjogren's syndrome (40-95%) and SLE (10-20%). Antibodies against SS-B are more commonly found in women, with a ratio of 29:1, and they are a significant marker in diagnosing these conditions.
These antibodies are key in diagnosing autoimmune diseases, particularly Sjogren's syndrome and SLE, and their presence can help guide clinical management and treatment decisions.
Test Type: Blood
Reporting: Third Day
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Yes. Book home collection when ordering online or call our team. Trained phlebotomists visit your address at the scheduled slot.
Most routine tests are reported same day after sample validation. Specialized tests may take longer — see your booking confirmation.
CoreLab follows NABL-aligned quality-assured pathology processes with structured SOPs, trained collectors, and MD pathologist oversight.
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