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When evaluating patients with signs and symptoms of an autoimmune tissue disease and a positive test for antinuclear antibodies (A), it's important to consider the presence of specific autoantibodies such as SS-A (Ro) and SS-B (La). These antibodies are commonly associated with several autoimmune conditions:
SS-A (Ro): Also known as Ro, this antigen is primarily associated with Sjogren's syndrome, where antibodies against SS-A are found in 40-95% of cases. They are also present in Systemic Lupus Erythematosus (SLE) in 20-60% of cases, primary biliary cirrhosis (around 20%), and occasionally in chronic active hepatitis.
SS-B (La): Known as La, this antigen is most often found in women (with a ratio of 29:1) and is strongly associated with Sjogren's syndrome (40-95%) and SLE (10-20%).
The presence of these antibodies can help in diagnosing autoimmune diseases like Sjogren's syndrome and SLE and assist in determining the appropriate course of treatment.
Yes. Book home collection when ordering online or call our team. Trained phlebotomists visit your address at the scheduled slot.
Most routine tests are reported same day after sample validation. Specialized tests may take longer — see your booking confirmation.
CoreLab follows NABL-aligned quality-assured pathology processes with structured SOPs, trained collectors, and MD pathologist oversight.
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